Is 3,3'-Diaminobenzidine toxic?

3,3'-Diaminobenzidine (DAB) is a hazardous substance classified as a Group 2B (probable carcinogen) by the International Agency for Research on Cancer (IARC) and is mutagenic. Inhalation can cause skin and eye irritation, allergic reactions, and respiratory problems; long-term exposure may pose health risks. Its toxicity increases upon metabolic activation. When handling, a respirator, chemical goggles, nitrile gloves, and protective clothing must be worn, and the operation must be carried out in a fume hood. The appropriate first aid procedures must be understood.

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