Is Diphenhydramine Hydrochloride an antihistamine? What are the dangers of taking an overdose?

Yes! Diphenhydramine Hydrochloride is an antihistamine, a type of medicine that prevents allergy symptoms. These symptoms include sneezing, runny nose, itching, watery eyes, and rashes or hives (skin welts or raised, red itchy bumps). Diphenhydramine HCl can also be used with other drugs to treat anaphylactic shock (also called anaphylaxis), a severe, life-threatening allergic reaction. The U.S. Food and Drug Administration (FDA) is warning that taking higher than recommended doses of the common over-the-counter (OTC) allergy medicine diphenhydramine (Benadryl) can lead to serious heart problems, seizures, coma, or even death.

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