What are the benefits of Dextran? Does it have any side effects?

Dextran possesses distinctive properties such as higher water adsorption capability, non-toxic, and ability to polymer cross-linking. This property improves the angiogenic responses, promotes cell proliferation, and augments the wound healing process, thereby facilitating enhanced skin regeneration. Moreover, it plays a vital role in reducing the removal of exudates, metabolic byproducts, and various undesirable substances from the wound area, thereby creating a conducive environment for the healing process. Dextran can stimulate the angiogenesis formation of the new blood vessels and safeguard the epidermis against ischemic damage.Some reports have shown adverse effects when used in therapeutical doses and some teratogenic effects have been demonstrated when used in large doses. The current LD50 reported in rats is 10700 mg/kg.

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