What is the mechanism of action of neomycin sulphate and hydrocortisone ear drops?

Neomycin sulphate and hydrocortisone ear drops are veterinary medicinal products possessing antibiotic and anti-inflammatory properties. They are indicated for the treatment of bacterial infections in the middle ear of large, medium and small domestic animals and poultry, caused by Gram-positive and Gram-negative bacteria (such as Staphylococcus aureus, Escherichia coli, Haemophilus species, Klebsiella species, Enterobacter species. Neomycin sulfate inhibits protein synthesis in bacterial cells, leading to bacterial death. Meanwhile, hydrocortisone exerts anti-inflammatory effects at the site of infection in animals.

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