What is the role of triphenylphosphine in drug delivery?

Triphenylphosphine is a lipophilic compound with mitochondrial targeting effect, that can easily pass through the biomembrane structure and bind to the mitochondrial membrane, precisely delivering drugs to mitochondria. For example, the chemical linking of mitochondria-targeting to transport DOX to mitochondria has successfully achieved the accurate induction of OS and apoptosis through the mitochondrial pathway in tumor cells.

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