What is the source of rutin? How effective is its antioxidant activity?

Rutin is a flavonol glycoside first isolated from Rutina graveolens. It comprises the aglycone quercetin and the disaccharide, rutinose, as its structural components. It exhibits a wide range of pharmacological benefits against various neurodegenerative disorders. It acts as an efficient free radical scavenger in a dose-dependent manner in neuronal cells overcoming oxidative and nitrosative stress. Rutin improves antioxidant enzymes and reduces proinflammatory cytokines apart from improving neuronal survival. Rutin is one of the best natural antioxidants in the known natural class. It has various pharmacological activities such as antibacterial, antiprotozoal, antitumor, antiinflammatory, antiallergic, antiviral, cytoprotective, vasoactive, hypolipidaemic, antiplatelet, antispasmodic, and antihypertensive.

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