What is the synthesis and toxicity of Coumalic acid?

Coumalic acid is a bright yellow prisms from methanol, a method to prepare coumalic acid comprising heating a solution in dichloroethane of malic acid and sulfuric acid or a solution in dichloroethane of malic acid and a perfluorosulfonic acid so as to convert the malic acid into a major amount of coumalic acid. Coumalic acid causes skin irritation and serious eye irritation.

You may like